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It has consequences in animals that happen to be similar to THC, a cannabinoid discovered naturally in cannabis, resulting in its software in artificial cannabis products and solutions like “authorized cannabis herbal incense mixes,” that happen to be bought legally as “incense” in certain countries but are labeled “not for human usage.”

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JWH-018, like many synthetic cannabinoids, is a complete agonist in the CB1 receptors in distinction to the partial agonist Δ9-THC. Because of this, damage mediated by CB1 receptor agonism can be far more severe than its partial agonist counterparts.